This Bubble Up Biscuit Pizza Casserole is a quick and comforting meal that’s perfect for busy weeknights. Fluffy biscuit pieces are baked with savory pizza sauce, gooey cheese, and all my favorite pizza toppings, creating a bubbly, golden-brown casserole that satisfies every time.
Why You’ll Love This Recipe
I love how simple and versatile this recipe is. It uses canned biscuit dough, which makes it fast and convenient, and I can easily switch up the toppings to match whatever I’m craving—or whatever I have in the fridge. It’s kid-friendly, crowd-pleasing, and it brings all the flavors of pizza in a cozy, casserole-style bake.
Ingredients
(Here’s a tip: Check out the full list of ingredients and measurements in the recipe card below.)
1 can (16.3 oz) refrigerated biscuit dough, cut into quarters
1 cup pizza sauce
1½ cups shredded mozzarella cheese
½ cup sliced pepperoni (or mini pepperoni)
½ cup cooked and crumbled Italian sausage (optional)
½ teaspoon Italian seasoning
¼ teaspoon garlic powder
2 tablespoons grated Parmesan cheese
2 tablespoons chopped fresh parsley (optional for garnish)
Directions
I preheat my oven to 375°F (190°C) and lightly grease a 9×13-inch baking dish.
I cut each biscuit into quarters and place them in a large mixing bowl.
I pour the pizza sauce over the biscuit pieces and toss them gently to coat.
I fold in 1 cup of the shredded mozzarella, half of the pepperoni, and the crumbled sausage if using.
I transfer the mixture to the prepared baking dish, spreading it out evenly.
I top with the remaining mozzarella, pepperoni, Parmesan cheese, Italian seasoning, and garlic powder.
I bake uncovered for 25–30 minutes or until the biscuits are puffed up and cooked through and the cheese is golden and bubbly.
I let it rest for 5 minutes, then sprinkle with chopped parsley before serving.
Servings and timing
This recipe makes about 6 servings. It takes approximately 10 minutes to prepare and 25–30 minutes to bake, with a 5-minute resting time before serving.
Variations
I sometimes swap out the pepperoni for cooked sautéed mushrooms and bell peppers for a veggie version. For a spicier kick, I like adding a few red pepper flakes or diced jalapeños. If I want a more indulgent casserole, I add extra cheese or mix in a spoonful of cream cheese to the sauce for a creamier base.
Storage/Reheating
Leftovers keep well in the refrigerator for up to 3 days. I store them in an airtight container. To reheat, I pop individual servings in the microwave for about 1–2 minutes or warm the whole dish in a 350°F oven until heated through (about 10–15 minutes). I avoid overbaking during reheating to keep the biscuits soft.
FAQs
How do I know when the biscuits are fully cooked?
I check that the biscuit pieces are puffed up and golden on top. I also insert a toothpick or knife into the center—if it comes out clean and there’s no raw dough, it’s done.
Can I make this casserole ahead of time?
Yes, I prepare the casserole and store it in the fridge (unbaked) for up to a day. When I’m ready, I bake it straight from the fridge, adding a few extra minutes to the cook time.
Can I use homemade biscuit dough?
Absolutely. I just make sure the dough is portioned into small pieces and baked until fully cooked through. It adds a more homemade touch to the dish.
What other cheeses work in this recipe?
Besides mozzarella, I like using cheddar, provolone, or even Monterey Jack for a twist. A blend of cheeses works great for a deeper flavor.
Can I freeze this casserole?
Yes, I let the baked casserole cool completely, then freeze portions in airtight containers. To reheat, I thaw it in the fridge overnight and warm it in the oven until hot.
Conclusion
Bubble Up Biscuit Pizza Casserole is one of my favorite go-to dinners when I want something hearty, comforting, and incredibly easy to make. It hits all the right notes—cheesy, saucy, and full of those classic pizza flavors—baked into a bubbly, pull-apart casserole. Whether I’m feeding the family or just indulging in a cozy night at home, this dish never disappoints.
This Bubble Up Biscuit Pizza Casserole is a comforting, family-friendly dish made with canned biscuit dough, pizza sauce, cheese, and customizable toppings. It’s a quick, easy, and satisfying twist on traditional pizza, baked into a bubbly casserole.
Ingredients
1 can (16.3 oz) refrigerated biscuit dough, cut into quarters
1 cup pizza sauce
1½ cups shredded mozzarella cheese
½ cup sliced pepperoni (or mini pepperoni)
½ cup cooked and crumbled Italian sausage (optional)
½ teaspoon Italian seasoning
¼ teaspoon garlic powder
2 tablespoons grated Parmesan cheese
2 tablespoons chopped fresh parsley (optional for garnish)
Instructions
Preheat oven to 375°F (190°C) and lightly grease a 9×13-inch baking dish.
Cut each biscuit into quarters and place them in a large mixing bowl.
Pour the pizza sauce over the biscuit pieces and toss gently to coat.
Fold in 1 cup of the shredded mozzarella, half of the pepperoni, and the crumbled sausage if using.
Transfer the mixture to the prepared baking dish and spread it out evenly.
Top with remaining mozzarella, pepperoni, Parmesan cheese, Italian seasoning, and garlic powder.
Bake uncovered for 25–30 minutes or until biscuits are puffed and cheese is golden and bubbly.
Let rest for 5 minutes, then sprinkle with chopped parsley before serving.
Notes
Swap pepperoni for sautéed veggies for variation.
Add red pepper flakes or jalapeños for a spicy version.
Use homemade biscuit dough if preferred.
Leftovers can be stored in the fridge for up to 3 days.
Reheat in the microwave or oven but avoid overbaking.
