Name: Chicken Alfredo Lasagna Roll Ups
Prep time: 25 min
Cook time: 30 min
Total time: 55 min
Cuisine: Italian-American
Ingredients: 8-10 lasagna noodles; 2 cups cooked shredded chicken; 1 cup ricotta cheese; 4 oz cream cheese (optional); 1 cup frozen chopped spinach, well drained; 1 cup shredded mozzarella cheese; 1 cup shredded colby jack cheese; 2 tbsp butter; 2 cloves garlic, minced; 1 ½ cups heavy cream; 1 cup grated Parmesan cheese; 1 tsp Cajun or Italian seasoning; Salt and pepper to taste

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I came across this chicken Alfredo lasagna roll ups recipe and it’s become one of my favorite comfort meals. Tender chicken, creamy ricotta, and Alfredo sauce, all rolled up in lasagna noodles and baked to golden perfection—it’s rich, cheesy, and surprisingly easy.

Why You’ll Love This Recipe

I love that I can have a hearty, satisfying dinner ready in about an hour. The rolls feel special yet they’re so simple to assemble. This one-pan dish is crowd-pleasing, freezer-friendly, and full of cheesy goodness that never disappoints.

ingredients

(Here’s a tip: Check out the full list of ingredients and measurements in the recipe card below.)
lasagna noodles
cooked shredded chicken
ricotta cheese
cream cheese (optional for added creaminess)
frozen chopped spinach, well drained
mozzarella cheese
colby jack cheese
butter
garlic, minced
heavy cream
parmesan cheese
Cajun or Italian seasoning
salt and pepper

directions

I start by cooking the chicken seasoned with olive oil and Cajun or Italian spices until golden, then dice it once it rests. In the same pan I melt butter and sauté garlic before whisking in heavy cream and Parmesan to make a creamy Alfredo sauce.
Meanwhile I boil lasagna noodles until al dente, drain them, and lay them flat to cool. For the filling, I mix ricotta, cream cheese, spinach, diced chicken, and half the shredded cheeses in a bowl.
Then I place about ½ cup of filling on each noodle, roll them up seam-side down in a greased 9×13 baking dish. I pour Alfredo sauce over the rolls, spooning into crevices, then sprinkle the remaining cheese on top. I bake uncovered at 375°F for about 35 minutes, until bubbly and golden.

Servings and timing

Prep time: about 25 minutes
Cook time: about 30 minutes
Total time: around 55 minutes
Servings: 6 servings, about 2 roll ups per person

Variations

If I’m using gluten-free ingredients, I swap in GF noodles and dairy-free cheeses. Veggies like mushrooms or zucchini mix well in the filling.

storage/reheating

I refrigerate leftovers in an airtight container for up to 3–4 days. To reheat I prefer baking at 350°F until warmed through; microwaving works too but may soften the sauce slightly.
For freezing, I assemble the roll ups (unbaked) in a freezer-safe dish, wrap tightly, and freeze up to 3–4 months. When ready to bake, I thaw in the fridge and bake as usual, adding a few extra minutes if still partially frozen.

FAQs

How long can I refrigerate leftovers?

I typically store leftovers in the fridge for up to 3–4 days in airtight containers.

Can I freeze the dish?

Absolutely! I freeze the assembled but unbaked rolls (wrapped tightly) for up to 3–4 months.

Do I need to thaw before baking from frozen?

I thaw them overnight in the fridge, but if still frozen I just bake a bit longer until heated through.

Can I make the Alfredo sauce from scratch?

Yes—I prefer homemade with butter, cream, garlic, and Parmesan, but a good jarred Alfredo also works well.

What substitutions work in the filling?

I sometimes use shredded turkey instead of chicken, or mix in sautéed veggies like spinach or mushrooms for extra flavor and nutrition.

Conclusion

I find this chicken Alfredo lasagna roll ups recipe both indulgent and practical. It delivers creamy, cheesy flavor with minimal fuss and is perfect for meal prep or family dinner. Let me know how your batch turns out—I always enjoy hearing feedback or swaps you tried!